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异菸腙是异菸肼的衍生物,化学名为异菸醯香草醛腙,(Isonicotinyl Vanillyl-Hydrazone)。1951年由全苏化学药物研究所ⅢykиHa和Ca30HOB二氏所合成,1953年苏联专家苏金娜氏首先应用于临床治疗结核病,我国上海信谊药厂于1956年试制成功。此药特点为疗效高,毒性低,副作用少。但国内关于应用异菸腙治疗肺结核病的文献报告,还不多见。本院由1957年12月开始试用,现将服药期间达三个月的35例进行初步分析。临床资料与病历选择一、病例的一般分析:男32例,女3例;年龄最大者46岁,最小者20岁,以25～35岁年龄阶段为最多。以浸润型最多16例,慢性纤维空洞型14例,
Isoniazid is a derivative of isoniazid, and its chemical name is isonicotinyl Vanillyl-Hydrazone. In 1951 by the Institute of Chemical and Surfactant ⅢykиHa and Ca30HOB two synthesized by the Soviet Union in 1953 Soviet experts first applied to the clinical treatment of tuberculosis, China’s Shanghai Xinyi Pharmaceutical Factory in 1956 trial success. This medicine is characterized by high efficacy, low toxicity and few side effects. However, the domestic literature on the application of isoniazid in the treatment of pulmonary tuberculosis is still rare. The hospital started trial in December 1957, now 35 cases during the medication period of three months for a preliminary analysis. Clinical data and medical records selection First, the general analysis of cases: 32 males and 3 females; the oldest 46 years old, the youngest 20 years old, 25 to 35 years of age as the most. In order to infiltrate up to 16 cases, 14 cases of chronic fibrous cavitation,