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目的观察无创辅助通气治疗顽固性心力衰竭患者的疗效。方法选取60例顽固性心力衰竭患者随机分为2组,均给予强心、利尿、镇静、扩血管、解痉平喘、拮抗神经内分泌等规范优化治疗,在此基础上,治疗组予无创双水平呼吸机辅助通气治疗6～10h/d,对照组予鼻导管或面罩吸氧6～10h/d。观察并比较分析治疗1周后及出院时的有效率、住院费用及住院天数。结果治疗组总有效率为93.8%(28/30),住院费用(6.8±1.7)千元,住院天数(9.5±3.7)d;对照组总有效率为73.3%(22/30),住院费用(9.8±2.3)千元,住院天数(15.5±4.3)d;两组总有效率、住院费用及住院天数比较,差异均有统计学意义(P<0.01)。结论顽固性心力衰竭患者药物治疗同时应用呼吸机辅助通气治疗较单纯药物治疗效果显著,且可降低住院费用,减少住院天数。
Objective To observe the curative effect of noninvasive assisted ventilation on patients with refractory heart failure. Methods Sixty patients with refractory heart failure were randomly divided into 2 groups. All patients were given optimal therapy such as cardioplegia, diuretic, sedation, vasodilatation, antispasmodic and antiasthmatic, antagonistic neuroendocrine. On the basis of this, the treatment group received noninvasive bi-level respiration Machine-assisted ventilation for 6 ~ 10h / d, the control group to nasal catheter or mask oxygen 6 ~ 10h / d. Observation and comparative analysis of 1 week after treatment and discharge efficiency, hospitalization and hospitalization days. Results The total effective rate was 93.8% (28/30), hospitalization cost (6.8 ± 1.7) thousand, hospitalization days (9.5 ± 3.7) days, and the control group was 73.3% (22/30) (9.8 ± 2.3) and hospitalization days (15.5 ± 4.3) d respectively. There was significant difference between the two groups in the total effective rate, hospitalization cost and hospitalization days (P <0.01). Conclusions The treatment of patients with refractory heart failure while using ventilator-assisted ventilation is more effective than simple drug therapy, and can reduce the cost of hospitalization and reduce the number of days of hospitalization.