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目的：探讨微波组织凝固在治疗口底鳞癌中的价值。方法：中山医科大学肿瘤医院头颈科自１９８９ 年至１９９３ 年应用微波组织凝固治疗方法对２６ 例口底鳞癌患者的原发灶进行治疗，其中Ⅰ期２ 例，Ⅱ期１１ 例，Ⅲ期１０ 例，Ⅳ期３ 例。在微波治疗前，先行颈清扫术；大部分患者同时行颈外动脉舌动脉结扎。６ 例Ⅲ、Ⅳ期患者还结合辅助放疗或／ 和化疗。结果：本组病例５ 年生存率为６１－５ ％ （１６／２６） ；其中Ⅰ期为１００ ％ ，Ⅱ期７２－７％ （８／１１） ，Ⅲ期５０ ％ （５／１０） ，Ⅳ期３３－３％ （１／３） 。有４ 例在２ 年内原发灶复发，占１５－４ ％ ；３ 例出现颈淋巴结转移，占１１－５ ％ ；３ 例出现远处转移，占１１－５ ％ 。创面出血、舌根后坠和呼吸困难是主要的术后并发症。结论：微波组织凝固应用于口底鳞癌原发灶的治疗，其生存率及复发情况与用传统手术方法治疗的结果接近，在保全口腔功能及面部外形方面优于传统治疗方法。
Objective: To explore the value of microwave tissue coagulation in the treatment of squamous cell carcinoma of the floor. METHODS: The Department of Head and Neck Surgery of Cancer Hospital of Sun Yat-sen University of Medical Sciences applied microwave tissue coagulation therapy from 1989 to 1993 to treat the primary lesions of 26 patients with ostial squamous cell carcinoma of the mouth, including 2 in stage I, 11 in stage II, and 10 in stage III. Example, three cases of stage IV. Prior to microwave therapy, neck dissection was performed first; most patients also underwent external carotid artery tongue ligation. Six patients of stage III and IV were also treated with adjuvant radiotherapy or/and chemotherapy. Results: The 5-year survival rate in this group was 61-5 % (16/26), of which stage I was 100%, stage II was 72-7% (8/11), stage III was 50% (5/10), IV. 33-3% (1/3) of the period. There were 4 cases of recurrence of primary lesions within 2 years, accounting for 15-4%; 3 cases of cervical lymph node metastasis, accounting for 11-5 %; 3 cases of distant metastasis, accounting for 11-5 %. Bleeding wounds, falling back of the tongue, and dyspnea are the major postoperative complications. Conclusion: Microwave tissue coagulation is applied to the treatment of primary squamous cell carcinoma of the mouth floor. The survival rate and recurrence of the tissue are similar to those obtained by traditional surgical methods. It is superior to the traditional treatment methods in preserving oral function and facial appearance.