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本文用表皮生长因子（EGF）作为判断肾损害及了解肾小管再生修复能力的指标，观察了25例窒息新生儿尿中EGF浓度的变化，结果表明：窒息新生儿普遍存在肾损害，且随着窒息程度的加重而加重，第3天达高峰，多数在1周内很快恢复正常，但重度窒息5分钟仍不恢复者可至1周。因此，尿EGF浓度的测定是一个有价值的判断窒息新生儿肾损伤程度、进展情况及小管损伤修复能力的指标。
In this paper, epidermal growth factor (EGF) as an indicator of renal damage and renal tubular regeneration to understand the ability to repair, observed 25 cases of neonatal asphyxia neonatal EGF concentration changes, the results show that asphyxia newborns widespread renal damage, and with Asphyxia exacerbated and aggravated, peaked on the third day, the majority of quickly returned to normal within 1 week, but severe asphyxia 5 minutes still can not be recovered to 1 week. Therefore, the determination of urinary EGF concentration is a valuable indicator to determine the extent of neonatal renal injury and progress of asphyxia and the ability of wound repair.