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目的将利多卡因应用于肝动脉药泵化疗镇痛效果观察,了解其疗效及其临床实用性。方法将肝动脉化疗66例随机分为实验组与对照组两组。两组均泵内注射多柔比星l0mg、脱氧脱氧氟脲苷250mg,实验组在肝动脉化疗前泵内注射2%利多卡因2ml。观察两组患者腹部疼痛缓解情况及生活质量情况。结果观察组疼痛缓解率及缓解程度均较对照组好转,两组具有显著差异(P<0.05)。整体生活质量有明显的改善(P<0.05)。结论利多卡因用于肝动脉药泵化疗具有良好的镇痛效果,可在临床推广应用。
Objective To observe the effect of lidocaine on the analgesic effect of hepatic artery pump chemotherapy to understand its curative effect and its clinical practicability. Methods 66 cases of hepatic artery chemotherapy were randomly divided into experimental group and control group. Both groups were injected with doxorubicin l0mg, deoxydeoxyfucoside 250mg, experimental group in the hepatic artery chemotherapy before injection of 2% lidocaine 2ml. Abdominal pain relief and quality of life in both groups were observed. Results The pain relief rate and the degree of remission in the observation group were all better than those in the control group, with significant differences between the two groups (P <0.05). Overall quality of life improved significantly (P <0.05). Conclusion lidocaine used for hepatic artery pump chemotherapy has good analgesic effect, which can be popularized and applied clinically.