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恶性胸水患者,生活质量明显下降,全身化疗效差,单纯放液可使蛋白质大量丢失而致病情迅速恶化。目前有效控制胸水最常用的方法是腔内灌注抗癌药物,笔者以羟基喜树碱(HCTP)联合高聚生胸腔灌注治疗36例老年晚期肺癌伴胸腔积液患者,效果良好,现报告如下。 临床资料:本组男23例,女13例;年龄60～82岁,平均68岁。均经病理、细胞学检查确诊,其中腺癌20例,鳞癌12例,小细胞癌4例。无明显心肝肾功能障碍,Karnofsky评分
Patients with malignant pleural effusion, quality of life decreased significantly, systemic chemotherapy is poor, a simple liquid can make a lot of protein loss and rapid deterioration of the disease. Currently the most commonly used method to effectively control pleural effusion is intracavitary infusion of anticancer drugs, the author of hydroxycamptothecin (HCTP) combined with high polychaete thoracic perfusion in 36 patients with advanced lung cancer with pleural effusion, the effect is good, are as follows. Clinical data: The group of 23 males and 13 females; aged 60 to 82 years, mean 68 years. All of them were diagnosed by pathology and cytology, including 20 cases of adenocarcinoma, 12 cases of squamous cell carcinoma and 4 cases of small cell carcinoma. No significant heart and kidney dysfunction, Karnofsky score