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目的:观察生肌通窍散I号术腔填塞的止血效果。方法:选取慢性鼻窦炎经Messerklinger手术者46例(79鼻),分为观察组24例(41鼻)和对照组22例(38鼻),观察组术毕术腔用生物止血海绵加生肌通窍散I号填塞,对照组术腔则用膨胀海绵填塞48h,观察2组患者术后,鼻腔渗血、头胀痛、鼻-鼻窦黏膜肿胀情况,以及术腔黏膜上皮化时间。结果:观察组患者术后,鼻腔渗血情况与对照组无明显差异,但观察组无对照组因抽除填塞物而发生出血及疼痛现象;患者术后头胀痛、术后鼻-鼻窦黏膜肿胀程度,观察组较对照组轻微并有显著差异性(P<0.01);2组患者术腔黏膜上皮化时间有显著差异,观察组优于对照组(P<0.01)。结论:生物止血海绵加生肌通窍散术腔填塞,有较好的止血作用,且局部反应轻微,在较好的患者耐受性,并对术腔黏膜上皮化有促进作用,值得进一步观察研究。
OBJECTIVE: To observe the hemostatic effect of Shengji Tongtong San I capsule. Methods: 46 patients (79 nasal mucosa) who underwent Messerklinger surgery were divided into observation group (n = 41) and control group (n = 22) (n = 38). The observation group was treated with biological hemostatic sponge plus muscle Tongqiao scattered No. I stuffing, the control group was inflated sponge stuffed 48h, observed two groups of patients after surgery, nasal bleeding, head pain, nasal sinus mucosal swelling, and mucosal epithelialization of the time. Results: There was no significant difference between the observation group and the control group in the postoperative bleeding of the nasal cavity and the control group. However, in the control group, there was no bleeding and pain in the control group due to the removal of the stuffing. In the patients with head pain and postoperative nasosinus mucosa The degree of swelling in the observation group was slightly and significantly different from that in the control group (P <0.01). The time of mucosal epithelization in the two groups was significantly different, and the observation group was superior to the control group (P <0.01). CONCLUSION: Bio-hemostatic sponge combined with Sheng Tong Tongqiao decoction has better hemostatic effect, less local reaction, better patient tolerance, and promoting mucosal epithelialization in the mucosa, which deserves further study .