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目的了解北京怀柔医院住院2型糖尿病患者降糖用药的情况,以指导临床合理用药。方法 2015年1月至6月对北京怀柔医院内分泌科收治的497例住院2型糖尿病患者进行问卷调查和抽血化验。分析降糖药物的使用情况,并比较新发2型糖尿病患者与既往2型糖尿病患者所用降糖药物的差异。结果 1胰岛素55.7%(277/497)、二甲双胍49.5%(246/497)和阿卡波糖30.2%(150/497)的使用率较高。2新发2型糖尿病患者中二甲双胍的使用率高于既往患者(χ~2=11.34,P<0.05),而胰岛素的使用率低于既往患者(χ~2=11.97,P<0.05)。3患者总体血糖达标率(Hb A1c<7%)为23.7%(118/497),其中新发2型糖尿病患者达标率低于既往患者血糖达标率,组间差异有统计学意义(χ~2=21.16,P<0.05)。结论北京怀柔医院住院2型糖尿病患者降糖治疗尚存在不足,总体血糖达标率不高,需进一步加强并规范2型糖尿病患者的降糖治疗。
Objective To understand the hypoglycemic effect of inpatients with type 2 diabetes mellitus in Beijing Huairou Hospital in order to guide clinical rational drug use. Methods From January to June 2015, 497 inpatients with type 2 diabetes mellitus admitted to Department of Endocrinology, Huairou Hospital of Beijing were investigated by questionnaires and blood tests. Analyze the use of hypoglycemic drugs, and compare the differences between the new-onset type 2 diabetes patients and those with previous type 2 diabetes mellitus. RESULTS 1 55.7% (277/497) of insulin, 49.5% (246/497) of metformin and 30.2% (150/497) of acarbose were highly used. Metformin was higher in patients with newly diagnosed type 2 diabetes than in previous patients (χ ~ 2 = 11.34, P <0.05), while insulin use was lower than in previous patients (χ ~ 2 = 11.97, P <0.05). 3, the overall rate of Hb A1c (7%) was 23.7% (118/497). The compliance rate of newly diagnosed type 2 diabetes patients was lower than that of previous patients, the difference was statistically significant (χ ~ 2 = 21.16, P <0.05). Conclusions The hypoglycemic treatment of type 2 diabetic patients in Beijing Huairou Hospital is still inadequate, and the overall blood glucose compliance rate is not high. It is necessary to further strengthen and standardize the hypoglycemic treatment of type 2 diabetic patients.