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目的 探讨血清CA12 5测定在活动性肺结核判定及疗效评估中的价值。方法 应用化学发光法分别对3 0例活动性肺结核治疗前、治疗后 2个月、4个月、6个月以及 3 0例非活动性肺结核和 3 0例健康体检者血清CA12 5进行测定。并对结果进行分析。结果 活动性肺结核治疗前血清CA12 5水平显著高于非活动性肺结核及健康体检者 (P <0 0 1)。活动性肺结核治疗前CA12 5水平显著高于治疗后各期测定值 (P <0 0 1) ,且治疗后血清CA12 5水平呈递减趋势。活动性肺结核治疗后 6个月血清CA12 5水平与非活动性肺结核比较无明显差异 ( P >0 0 5 )。结论 血清CA12 5测定可作为判定活动性肺结核及评估疗效的可靠指标
Objective To investigate the value of determination of serum CA12 5 in the assessment of active pulmonary tuberculosis and its efficacy. Methods The levels of serum CA12 5 in 30 active pulmonary tuberculosis patients before treatment, 2 months, 4 months and 6 months after treatment, 30 cases of non-active tuberculosis and 30 healthy subjects were measured by chemiluminescence method. And analyze the result. Results The level of serum CA12 5 in active tuberculosis before treatment was significantly higher than those in inactive tuberculosis and healthy subjects (P <0.01). The level of CA12 5 in active tuberculosis before treatment was significantly higher than that in each period after treatment (P <0.01), and the level of serum CA12 5 showed a decreasing trend after treatment. There was no significant difference in serum CA12 5 levels between inactive tuberculosis and inactive tuberculosis 6 months after active tuberculosis (P> 0.05). Conclusion Serum CA12 5 determination can be used as a reliable indicator of active pulmonary tuberculosis and evaluation of curative effect