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目的:观察在基础治疗上配合穴位注射联合梅花针与配合西药治疗小儿植物状态的临床疗效差异。方法:48例植物状态患儿随机分为观察组和对照组,各24例。两组在经颅磁刺激治疗仪、导平治疗仪及按摩治疗的基础上,观察组采用穴位注射及梅花针叩刺,将醒脑静注射液、鼠神经生长因子注射液、单唾液酸四己糖神经节苷脂钠注射液、复方丹参注射液两两分为一组,共6组,每组连续使用10天,分别注射于百会、涌泉、风府、哑门等穴,每穴0.5mL,每天1次,联合梅花针叩刺背部督脉及夹脊穴;对照组采用胞磷胆碱钠注射液、甘露醇注射液、地塞米松注射液静脉点滴。两组均每天治疗1次,20天为一疗程,共治疗3个疗程。分别于治疗20天、40天、60天后观察两组临床疗效、植物状态评分和平均痊愈时间。结果:治疗20天、40天、60天后观察组有效率分别为58.3%(14/24)、70.8%(17/24)、79.2%(19/24),对照组分别为20.8%(5/24)、45.8%(11/24)、58.3%(14/24),观察组疗效均优于对照组(P<0.01,P<0.05);两组治疗20天、40天、60天后各时间点植物状态评分均较治疗前明显提高(均P<0.05),观察组治疗后各时间点较对照组提高更明显(3.34±2.41vs 2.64±1.56,6.20±1.46vs 4.34±1.64,11.26±2.63vs8.75±2.18,均P<0.05);观察组平均痊愈时间为(45.67±16.24)天,明显短于对照组的(55.34±4.57)天(P<0.05)。结论:基础治疗配合穴位注射联合梅花针叩刺治疗小儿植物状态疗效可靠。
Objective: To observe the difference of clinical curative effect between basic acupuncture and acupoint injection combined with plum acupuncture and western medicine in treating children’s plant state. Methods: 48 cases of children with vegetative state were randomly divided into observation group and control group, each 24 cases. On the basis of transcranial magnetic stimulation therapy, guided therapy and massage therapy, the two groups were treated with acupuncture at acupoints and acupuncture points by acupuncture at Xinghuajing injection, mouse nerve growth factor injection, monosialin Sugar ganglioside sodium injection, compound Danshen injection was divided into two groups, a total of 6 groups, each group for 10 consecutive days, were injected in Baihui, Yongquan, wind House, dumb door and other points, each hole 0.5mL, 1 times a day, combined with plum needle tapping the back of Du and Jiaji points; control group using citicoline sodium injection, mannitol injection, dexamethasone injection intravenously. Two groups were treated once a day, 20 days for a course of treatment, a total of 3 courses of treatment. The clinical efficacy, plant status score and average recovery time of the two groups were observed after 20 days, 40 days and 60 days respectively. Results: The effective rates of the observation group after treatment for 20 days, 40 days and 60 days were 58.3% (14/24), 70.8% (17/24) and 79.2% (19/24), respectively, and those in the control group were 20.8% (5 / (P <0.01, P <0.05). In the two groups, the time of treatment at 20 days, 40 days and 60 days after treatment was significantly higher than that of the control group (45.8%, 11.3%, 58.3% (P <0.05). The observation group improved more significantly than the control group at each time point after treatment (3.34 ± 2.41 vs 2.64 ± 1.56,6.20 ± 1.46 vs 4.34 ± 1.64,11.26 ± 2.63 vs8.75 ± 2.18, all P <0.05). The average recovery time in the observation group was (45.67 ± 16.24) days, which was significantly shorter than that in the control group (55.34 ± 4.57) days (P <0.05). Conclusion: The basic treatment combined with acupuncture point injection combined with plum blossom needle treatment of infantile plant state curative effect is reliable.