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近年来学者发现,多形性腺瘤基因1的激活和表达与多形性腺瘤及其他唾液液肿瘤的发生密切相关。多形性腺瘤基因1具有转录因子活性,通过对下游靶基因的表达调控而发挥生物学功能。对多形性腺瘤基因1及其相关基因的功能以及其在多形性腺瘤发病机制中的作用研究,在口腔颌面肿瘤领域具普遍指导意义。
In recent years, scholars have found that the activation and expression of polymorphic adenoma gene 1 is closely related to the occurrence of pleomorphic adenoma and other salivary tumors. Polymorphic adenoma gene 1 has transcription factor activity and exerts biological functions by regulating the expression of downstream target genes. The research on the function of gene 1 and related genes of pleomorphic adenoma and its role in the pathogenesis of pleomorphic adenoma is of general guiding significance in the field of oral and maxillofacial tumors.