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目的探讨高血压并发脑梗死患者的血液红细胞形态的改变。方法用电镜扫描的方法观察32例高血压患者和32例高血压并发脑梗死患者的红细胞形态变化。结果高血压并发脑梗死患者的红细胞出现口型、嵴型、类球形等形态异常的红细胞检出率明显高于对照组(正常人)(<0.01)和高血压患者组(P<0.05)。结论高血压患者的红细胞形态出现异常是患者发生脑梗死的原因之一,因此在对高血压患者的防治中,除了应用降压、抗凝药物之外,还要使用促进红细胞形态正常化的药物,以达到预防发生脑梗死的目的。
Objective To investigate the changes of erythrocyte morphology in patients with hypertension complicated by cerebral infarction. Methods Electron microscopy was used to observe the morphological changes of erythrocytes in 32 hypertensive patients and 32 hypertensive patients with cerebral infarction. Results The detection rate of erythrocytes with abnormal morphology of erythrocytes in hypertensive patients with cerebral infarction was significantly higher than that in control group (<0.01) and hypertension group (P <0.05). Conclusion Abnormal erythrocyte morphology in hypertensive patients is one of the causes of cerebral infarction in patients. Therefore, in the prevention and treatment of patients with hypertension, in addition to antihypertensive and anticoagulant drugs, drugs that promote the normal morphology of red blood cells , In order to achieve the purpose of preventing cerebral infarction.