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目的比较保留乳房手术与改良根治术对早期乳腺癌预后的影响。方法回顾性分析安徽宿州市立医院肿瘤外科2005年6月-2011年6月经保留乳腺手术治疗的50例早期乳腺癌患者临床相关资料,并与同期在该科行改良根治术50例早期乳腺癌患者进行临床对比分析。结果保乳手术治疗不仅没有增加患者的局部复发率、转移率、病死率,且生存率与同期实施的改良根治术相当,并且保持了患者良好的乳房外形。结论在充分严格掌握保乳治疗适应证的前提下,规范手术方式,术后正规的辅助治疗如放化疗及内分泌治疗,不仅可治疗肿瘤,而且能明显提高患者的生活质量,是一种治疗早期乳腺癌比较理想的方法。实践证明对于早期乳腺癌,保乳手术是-种切实可行且值得推广的一种手术方式。
Objective To compare the effect of conservative breast surgery and modified radical mastectomy on the prognosis of early breast cancer. Methods The clinical data of 50 cases of early breast cancer treated with preserved breast surgery from June 2005 to June 2011 in Department of Oncology, Suzhou Municipal Hospital of Anhui Province were retrospectively analyzed. In the same period, 50 patients with early stage breast cancer underwent modified radical mastectomy Clinical comparative analysis. The results of breast-conserving surgery not only failed to increase the local recurrence rate, metastasis rate and mortality of patients, but the survival rate was the same as the modified radical operation performed in the same period and maintained the good breast shape of patients. Conclusion Under the premise of fully and strictly controlled indications of breast-conserving treatment, it is not only able to treat the tumor but also to improve the quality of life of the patients, which is an early stage of treatment under the premise of normalizing the operation mode and postoperative formal adjuvant therapy such as radiochemotherapy and endocrine therapy. Breast cancer is the ideal method. Practice has proved that for early breast cancer, breast-conserving surgery is - a practical and worth promoting a surgical approach.