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目的:探讨去氧孕烯炔雌醇片(妈富隆)在宫腔镜子宫内膜息肉(EP)切除术后的临床疗效。方法:186例EP患者均接受宫腔镜下子宫内膜息肉电切除术,术后病理诊断均为良性子宫内膜息肉,其中94例(观察组)术后口服妈富隆治疗6个月,另92例(对照组),术后未服药物。随访12个月,观察月经量、EP复发、月经周期情况。结果:(1)月经量:观察组术后月经量明显少于对照组,差异有统计学意义(P<0.05)。(2)息肉复发情况:对照组复发11例(11.96%),观察组复发6例(6.38%)。差异有统计学意义(P<0.05)。(3)月经周期:对照组有19例患者表现为月经不规则,而观察组仅4例表现为偶发的月经间期少量出血,差异有统计学意义(P<0.05)。结论:TCRP术后口服妈富隆可有效改善月经状况,减少子宫内膜息肉复发。
Objective: To investigate the clinical effect of ethinyl ethinyl estradiol (Marvelon) after hysteroscopic endometrial polyps (EP) resection. Methods: 186 cases of EP patients underwent hysteroscopic resection of endometrial polyps, pathological diagnosis of benign endometrial polyps, of which 94 cases (observation group) after oral Marvulon treatment for 6 months, and the other 92 cases (control group), no medication after surgery. Followed up for 12 months, observed menstrual flow, EP recurrence, menstrual cycle. Results: (1) Menstrual volume: The postoperative menstrual flow in the observation group was significantly less than that in the control group, with significant difference (P <0.05). (2) The recurrence of polyp: The control group recurred in 11 cases (11.96%), and the observation group recurred in 6 cases (6.38%). The difference was statistically significant (P <0.05). (3) Menstrual cycle: In the control group, 19 patients showed irregular menstruation, while in the observation group, only 4 patients showed occasional small amount of bleeding in the intermenstrual period. The difference was statistically significant (P <0.05). Conclusion: The oral administration of Marvelon after TCRP can effectively improve the menstrual status and reduce the recurrence of endometrial polyps.