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自本世纪初以来已认识到,充血性心力衰竭可导致肺功能减退,尤其是最大肺活量(FVC)和1秒用力呼气量(FEV_1)减低。但对于 FVC 和 FEV_1预测心血管病变的重要作用缺乏应有的评价。研究表明,FVC 减低预示发生心肌梗塞、猝死、冠状动脉病和高血压的危险性增大、总体病死率升高。另 FEV_1与体育活动量和 HDL 胆固醇水平呈正相关。体育活动量大、HDL 值高者肺功能良好。肺功能减退与肥胖也有关联。怎样解释这些现象和肺功能与心血管系统疾病的关系呢?首先,肺功能的呼吸量测定指标高度相关,
It has been recognized since the beginning of this century that congestive heart failure can lead to hypothyroidism, especially a decrease in maximum vital capacity (FVC) and forced expiratory volume in 1 second (FEV 1). However, the important role of FVC and FEV-1 in predicting cardiovascular disease is lacking. Studies have shown that reduced FVC predicts increased risk of myocardial infarction, sudden death, coronary artery disease and hypertension, the overall case fatality rate. The other FEV_1 was positively correlated with physical activity and HDL cholesterol. Large amount of physical activity, high HDL lung function is good. Lung dysfunction is also associated with obesity. How to explain these phenomena and the relationship between pulmonary function and cardiovascular disease? First of all, pulmonary function of respiratory index is highly correlated,