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目的:描述中枢神经系统炎性脱髓鞘性假瘤的临床表现,探讨该病的病理学特征以及MRI诊断价值,以期加强对本病的认识并提高诊断的正确性。方法:对2例经手术病理证实中枢神经系统炎性脱髓鞘性假瘤进行MRI检查,对其临床表现、影像学表现进行了回顾性分析。结果:MRI显示2例病变均表现为局限性肿块呈均匀长T1、长T2信号,临近未见伴有多发病灶。术前均被误诊为胶质瘤,经手术切除病变,病理证实为中枢神经系统炎性脱髓鞘性假瘤。结论:中枢神经系统炎性脱髓鞘性假瘤的临床和影像学诊断较为困难,常将本病误诊为肿瘤,此时可以先使用激素试验治疗,以避免手术或放射治疗造成的严重损伤。
Objective: To describe the clinical manifestations of inflammatory demyelinating pseudotumor in the central nervous system, to explore the pathological features of the disease and the diagnostic value of MRI in order to enhance the understanding of the disease and improve the correctness of the diagnosis. Methods: MRI findings of 2 cases of central nervous system inflammatory demyelinating pseudotumor confirmed by surgery and pathology were analyzed retrospectively. The clinical manifestations and imaging findings were analyzed retrospectively. Results: MRI showed two cases of lesions showed localized lesions were uniform long T1, T2 signal, with no adjacent to multiple lesions. All patients were misdiagnosed as gliomas preoperatively, and the lesions were removed by surgery. The pathological findings were inflammatory demyelinating pseudotumor of the central nervous system. Conclusion: The clinical and imaging diagnosis of inflammatory demyelinating pseudotumor of the central nervous system is more difficult. The disease is often misdiagnosed as a tumor. At this time, hormone therapy can be used to avoid serious injury caused by surgery or radiotherapy.