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目的:探讨细针吸取细胞学检查对涎腺黏液表皮样癌的诊断价值。方法:回顾性分析经组织学证实的黏液表皮样癌15例患者的细针吸取细胞学涂片资料,并对细胞学误诊原因进行总结。结果:黏液表皮样癌的细胞学诊断准确性取决于其组织学分级,高分化黏液表皮样癌,吸出物为大量黏液、可见少量黏液细胞,因细胞量少,诊断准确率较低。中分化黏液表皮样癌镜下见3种细胞成分,以黏液细胞、表皮样细胞和中间细胞为特征,定性分类准确率高。低分化黏液表皮样癌肿瘤细胞表现为大量中间型鳞状细胞,伴或不伴有产生黏液的细胞,核的多形性明显,定性准确率100%,分类较低。结论:黏液表皮样癌的细胞学表现有特征性,细胞学检查对黏液表皮样癌具有一定的诊断价值,但需与多形性腺瘤、黏液囊肿等鉴别。
Objective: To investigate the diagnostic value of fine needle aspiration cytology in mucoepidermoid carcinoma of salivary gland. Methods: A retrospective analysis of histologically confirmed mucoepidermoid carcinoma in 15 patients with fine needle aspiration cytology smears, and the reasons for cytological misdiagnosis were summarized. Results: The accuracy of cytological diagnosis of mucoepidermoid carcinoma depends on its histological grade, highly differentiated mucoepidermoid carcinoma, aspirate is a large number of mucus, a small amount of mucus cells can be seen, because of the small amount of cells, the diagnostic accuracy is low. In the differentiated mucoepidermoid carcinoma, three kinds of cellular components are seen under the microscope, which are characterized by mucous cells, epidermoid cells and middle cells, and have high qualitative classification accuracy. Poorly differentiated mucoepidermoid carcinoma tumor cells showed a large number of intermediate squamous cells, with or without mucus-producing cells, the nuclear pleomorphism was obvious, the qualitative accuracy of 100%, classification is low. Conclusions: The cytological findings of mucoepidermoid carcinoma are characteristic. Cytological examination has some diagnostic value for mucoepidermoid carcinoma, but it needs to be differentiated from pleomorphic adenoma and mucinous cyst.