应激性溃疡在重症患者是一常见的临床问题,其出血死亡率很高.然而,自七十年初以来应激性溃疡所致大出血的发生率已显著降低,这与抗酸剂和甲氰咪胍的应用有关,此外营养也可能起一定作用.Barboriak等提出,饥饿鼠对应激性溃疡的敏感性增加,而给予营养后,鼠的溃疡发生率显著低于对照组.要素饮食的作用优于甲氰咪胍,其原因尚不清楚.另一方面, Stress ulcers are a common clinical problem in critically ill patients and have a high rate of bleeding mortality However, the incidence of major bleeding due to stress ulcer has dropped significantly since the early seventies, which is related to antacids and methyl cyanide In addition to the application of the guanidine, in addition to nutrition may also play a role.Barboriak et al proposed hunger mice increased susceptibility to stress ulcer, while giving nutrition, rat ulcer incidence was significantly lower than the control group. The reason for cimetidine is not yet clear. On the other hand,