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由戊二醛脱毒的聚合破伤风类毒素，经高压液相层析及聚丙烯酰胺凝胶电泳分析，类毒素中多聚体含量占８１．９％以上，多聚体分子量为８００ｋＤ，常规破类多聚体仅占有２．２４％。聚合破类免疫豚鼠后，平均心血抗体单位达２ＩＵ／ｍｌ，常规破类仅为０．７５ＩＵ／ｍｌ（Ｔ＝１３．１５，Ｐ＜０．００１），聚合破类免疫马匹后所诱发的抗体水平较常规抗原的高。
The polyvalent tetanus toxoid detoxified by glutaraldehyde was analyzed by high pressure liquid chromatography and polyacrylamide gel electrophoresis. The toxoid contained more than 81.9% of polymer and the polymer had a molecular weight of 800kD. Conventional Broken polymer only occupy 2.24%. After the immune guinea pigs were disrupted by immunization, the average unit of blood antibody reached 2 IU / ml, the routine breaking class was only 0.75 IU / ml (T = 13.15, P <0.001) Higher levels of conventional antigens.