论文部分内容阅读
目的了解孤立性心肌致密化不全(INVM)的临床特征、治疗现状及长期预后。方法收集2004年1月至2007年8月河南省人民医院诊治的28例INVM患者的临床资料及治疗情况并进行长期随访。结果INVM主要症状有:气短25例(89.29%),心电图异常26例(92.85%),左室功能下降26例(92.85%)。致密化不全的主要部位是心尖部20例(71.43%),心尖部血栓3例(10.71%),心包积液6例(21.43%)。21例接受了随访,平均随访28.43个月,死亡2例(9.52%),因心力衰竭而需要反复住院治疗6例(28.57%),但治疗后心功能有所改善[(3.0±1.02)级对(2.11±0.66)级,P<0.01]。结论INVM患者临床表现缺乏特异性,心脏超声检查有助于诊断,本组患者预后良好。
Objective To investigate the clinical features, treatment status and long-term prognosis of isolated myocardial hypertrophy (INVM). Methods The clinical data and treatment of 28 patients with INVM diagnosed and treated in Henan Provincial People’s Hospital from January 2004 to August 2007 were collected and followed up for a long term. Results The main symptoms of INVM were: shortness of breath in 25 cases (89.29%), abnormal electrocardiogram in 26 cases (92.85%) and left ventricular dysfunction in 26 cases (92.85%). The main parts of densification were apical 20 cases (71.43%), apical thrombus in 3 cases (10.71%) and pericardial effusion in 6 cases (21.43%). Twenty-one patients were followed up for an average of 28.43 months with two deaths (9.52%) and six hospitalizations (28.57%) due to heart failure. However, their cardiac function improved after treatment (3.0 ± 1.02) For (2.11 ± 0.66) grade, P <0.01]. Conclusion The clinical manifestations of INVM lack of specificity, echocardiography is helpful in the diagnosis of this group of patients with good prognosis.