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目的:探讨降钙素原(PCT)水平检测对评估重症肺炎行机械通气治疗患者预后的临床价值。方法:以2012年1月至2013年10月因重症肺炎在粤北人民医院ICU住院且行有创机械通气治疗43例患者为研究对象,记录PCT、体温峰值、红细胞沉降率(ESR)、C反应蛋白(CRP)、白细胞计数(WBC)、中性粒细胞计数(NEUT)、左室射血分数(LVEF)、呼吸机使用天数,了解PCT水平与各项住院指标的关系。结果:PCT明显升高组(A组)与PCT一般升高组(B组)比较,体温峰值、ESR、WBC、NETU、CRP、呼吸机使用时间均显著升高,LVEF明显减低(P均<0.05)。PCT水平与体温峰值、ESR、WBC、NEUT比值、CRP、呼吸机使用天数呈正相关,与LVEF呈负相关。结论:PCT水平的检测能较好地评估重症肺炎患者预后、脏器功能。
Objective: To investigate the clinical value of procalcitonin (PCT) test in assessing the prognosis of patients with severe pneumonia treated with mechanical ventilation. Methods: From January 2012 to October 2013, 43 patients with severe pneumonia admitted to ICU of Guangdong North People’s Hospital underwent mechanical ventilation were enrolled in this study. PCT, peak body temperature, erythrocyte sedimentation rate (ESR), C reaction CRP, WBC, NEUT, LVEF and days of ventilator, and to understand the relationship between PCT level and various inpatients. Results: The body temperature peak, ESR, WBC, NETU, CRP, ventilator use time were significantly increased, while LVEF was significantly lower in PCT elevated group (group A) compared with PCT general increase group (group B) 0.05). PCT levels and body temperature peak, ESR, WBC, NEUT ratio, CRP, ventilator days was positively correlated with LVEF was negatively correlated. Conclusion: The detection of PCT level can better assess the prognosis and organ function of patients with severe pneumonia.