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我科1986年2月至1991年4月采用由丝裂霉素、长春新碱(或足叶乙甙)、顺铂组成联合化疗方案(简称MOP 或MEP 方案)治疗50例晚期肺腺癌,现报告如下。临床资料一般资料:本组50例均为初治病人,经病理或细胞学检查证实为肺腺癌,病期均为Ⅲ、Ⅳ期。其中男39例,女11例,中位年龄55(29~69)岁。MOP 方案治疗30例,MEP 方案治疗20例,体质状态按Karnofsky 法评分(简称卡氏评分),40~60分者7例,MOP 组4例、MEP组3例,70~90分者43例、MOP 组26例、MEP 组17例。
In our department from February 1986 to April 1991, 50 patients with advanced lung adenocarcinoma were treated with mitomycin, vincristine (or etoposide), and cisplatin combined chemotherapy (MOP or MEP). The report is as follows. Clinical data General data: 50 patients in this group were untreated patients. Lung adenocarcinoma was confirmed by pathological or cytological examination. The stage of disease was stage III and IV. There were 39 males and 11 females, with a median age of 55 (29 to 69) years. There were 30 cases treated with MOP regimen, 20 cases treated with MEP regimen, physical condition according to Karnofsky’s method (Kappe scale), 7 cases with 40 to 60 points, 4 cases with MOP group, 3 cases with MEP group, and 43 cases with 70 to 90 points. 26 patients in the MOP group and 17 patients in the MEP group.