Reye氏综合征一般被视为儿科疾病,其临床特征多先有病毒感染的前驱症状,接着出现呕吐、脑病并伴有肝功能障碍。本文作者报道4例Reye氏综合征发生于非儿科年龄组,年龄16～23岁。所有病例于发病前均有病毒感染史,血清学检查证明例_1、例_3与流感病毒B,例_2与水痘病毒有关,例_4疑与流感病毒B有关。约于感染后1周突然出现恶心、呕吐,继而表现为烦躁不安、错乱、奇异行为、焦虑与思睡交替,最后进入嗜睡或昏迷。体检发现肝脏肿大,神经系统检查均呈弥 Reye’s syndrome is generally considered a pediatric disorder, with more clinical features than the prodromal symptoms of viral infection, followed by vomiting, encephalopathy and liver dysfunction. The authors report 4 cases of Reye’s syndrome occurred in non-pediatric age group, aged 16 to 23 years old. All cases before the onset of a history of viral infection, serological examination showed cases _1, cases _3 and influenza B, cases _2 and varicella-related, cases _4 suspects and influenza B related. About 1 week after infection, nausea and vomiting suddenly appeared, followed by irritability, confusion, strange behavior, anxiety and sleepiness alternating, and finally into drowsiness or unconsciousness. Physical examination found that the liver enlargement, neurological examination showed Mi