先证者　女 ,9岁 ,发作性双下肢疼痛 1年半。发作时突然出现双膝关节及以下疼痛难忍 ,持续 10～ 2 0分钟后逐渐缓解并入睡 ,醒来一切正常。发作时间均在下午 7～ 8点 ,每次发作后均入睡 ,间隔时间为 5～ 15天 ,发作时不伴意识障碍 ,无四肢抽搐。先证者之妹　 7岁半 ,发作性双下 The proband female, 9 years old, episodes of pain in both lower extremities 1 and a half years. A sudden onset of bilateral knees and the following pain was unbearable, sustained 10 ~ 20 minutes and gradually ease and fall asleep, wake up everything is normal. Attack time in the afternoon 7 to 8 points, each episode after falling asleep, interval is 5 to 15 days, episodes without disturbance of consciousness, no limbs convulsions. The proband’s sister 7 years and a half, paroxysmal double