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本文报道2例糜烂性扁平苔藓(LP)伴潜在性HBV感染具有循环抗表皮细胞核抗体的患者.例1.女性,64岁,口腔粘膜糜烂性LP及四肢LP皮损伴慢性肝炎早期硬化,HBsAg阴性,但抗HBs及抗HBc抗体阳性.例2.女性,53岁,口腔粘膜糜烂性LP及左颞部基底细胞癌(经病理证实),HBsAg阴性,但抗HBs及抗EBVIgG抗体阳性.2例患者的损害病理检查均示LP改变.直接免疫荧光(DIF)检查示表皮细胞核内有斑点状IgG沉积.间接免疫荧光(IIF)检查示:以大鼠肝为底物抗核抗体(ANA)阴性,以猴食道为底物ANA阳性.
This article reports 2 patients with erosive lichen planus (LP) with potential HBV infection who have circulating anti-epidermal cell nuclear antibodies.Example 1. Female, age 64, oral mucosal erosive LP and LP extremities with early hepatic cirrhosis, HBsAg Negative, but positive for anti-HBs and anti-HBc antibodies Example 2. Female, age 53, with oral mucosal erosive LP and left-sided basal cell carcinoma (pathologically confirmed), negative for HBsAg but positive for anti-HBs and anti-EBV IgG antibodies .2 Pathological examination of patients with lesions showed changes of LP.Immune immunofluorescence (DIF) examination showed speckled IgG deposition in the nucleus of the epidermis.Indirect immunofluorescence (IIF) examination showed that rat liver-specific antinuclear antibody (ANA) Negative, with monkey esophagus as substrate ANA positive.