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聚合物胶束作为药物载体具有很多优良的性能,如体内外稳定性高、良好的生物相容性、难溶性药物的增溶作用等。本文从聚合物胶束的类型、聚合物胶束的载药方法和聚合物胶束在药物增溶作用、被动靶向、主动靶向及基因治疗药物载体中的应用等三个方面综述了近几年的研究发展概况。
Polymer micelles as a drug carrier has many excellent properties, such as high stability in vitro and in vivo, good biocompatibility, solubilization of insoluble drugs and so on. In this paper, the types of polymer micelles, the drug loading method of polymer micelles and the application of polymer micelles in drug solubilization, passive targeting, active targeting and gene therapy drug carriers are reviewed in this paper. Years of research and development profiles.