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氨基精甙类（AminoglycosideAG）抗生素由于对需氧革兰氏阴性（G－）杆菌具有强大的抗菌活性，因此是临床上治疗G-杆菌感染的重要药物。部分品种对金葡菌具有很强的抗菌活性。链霉素作为一线抗结核药早在1944年就已被发现并用于治疗结核病。但AG的肾毒性损伤和耳毒性则不容忽视
AminoglycosideAG antibiotics are clinically important drugs for the treatment of G-bacilli due to their strong antibacterial activity against aerobic gram-negative (G-) bacilli. Some varieties of Staphylococcus aureus has a strong antibacterial activity. As a first-line anti-TB drug, streptomycin was discovered as early as 1944 and used to treat tuberculosis. But AG nephrotoxicity and ototoxicity can not be ignored