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据《美国医学论坛报》1994年6月16日报道Martens医师认为一种非介入性胎儿染色体分析虽尚处于试验阶段,它检测染色体异常的准确率却高达95％,可替代大多数初期羊膜穿刺检查。随羊膜穿刺次数减少,因穿刺而引致流产的人数也减少。 这项新检测方法只需孕妇的血样,用荧光标记DNA探针检测唐氏(Down)综合征持有的21号染色体三体型异常,5小时即出结果。而羊膜穿刺检查需8～10日出结果。
According to the United States Medical Tribune June 16, 1994 report, Martens doctors believe that although a non-interventional fetal chromosome analysis is still in the experimental stage, it detects chromosomal abnormalities as high as 95% accuracy, and can replace most of the initial amniocentesis an examination. As the number of amniocentesis decreased, the number of abortions due to punctures also decreased. The new assay, which uses only blood samples from pregnant women, detects chromosomal trisomy 21 on the Down syndrome using a fluorescently labeled DNA probe and produces the result at 5 hours. The amniocentesis examination required 8 to 10 results.