目的通过对出生缺陷的监测结果进行分析,掌握出生缺陷的发生情况、变化趋势、分布特征及其影响因素,为制定预防措施提供科学依据。方法对我区2006~2012年的出生缺陷监测资料进行回顾性分析。结果围产儿出生缺陷的发生率为70.10/万;出生缺陷发生率顺位的前五位依次是多指、先心病、先天性脑积水、总唇裂、外耳其他畸形;出生缺陷的发生率城市高于农村,产妇30岁及以上年龄组高于30岁以下年龄组。结论广泛开展防出生缺陷知识和优生优育知识宣传教育,加强孕前孕期保健、遗传咨询和提高产前诊断技术,适时终止妊娠,是降低出生缺陷发生率的关键。 Objective To analyze the monitoring results of birth defects and to understand the occurrence, changing trend, distribution characteristics and influential factors of birth defects, and to provide a scientific basis for making preventive measures. Methods The data of birth defects monitoring from 2006 to 2012 in our district were retrospectively analyzed. Results The incidence of perinatal birth defects was 70.10 / million. The top five birth defects were multifamily, congenital hydrocephalus, total cleft lip and other malformations of the outer ear. The incidence of birth defects was lower in cities In rural areas, males aged 30 years and over were higher than those under 30 years old. Conclusion It is the key to reduce the incidence of birth defects by extensively educating birth control and prenatal and postnatal care knowledge, strengthening prenatal care, genetic counseling and prenatal diagnosis, and timely termination of pregnancy.