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目的 :探讨围生期心肌病的病因。方法 :应用原位 PCR法对 2例 1 4、1 5年前临床诊断为围生期心肌病患者的心肌活检的石蜡切片进行柯萨奇 B组病毒 ( CVB)的检测。结果 :2例患者的心肌活检组织中 CVB- RNA均显示阳性信号。结论 :CVB感染可能是围生期心肌病的病因之一。
Objective: To investigate the etiology of perinatal cardiomyopathy. Methods: Coxsackie B virus (CVB) was detected in 2 paraffin sections from 2 myocardial biopsies of patients with perinatal cardiomyopathy who were diagnosed as perinatal cardiopulmonary disease 14.5 years ago. Results: The positive signals of CVB-RNA in myocardial biopsy of 2 patients were all positive. Conclusion: CVB infection may be one of the causes of perinatal cardiomyopathy.