在60年代初,Gott和他的同事研究电荷对塑料所引起血栓的影响。Abramson早就发现了血液的重要组分是带负电的。Sawyer又发现血管的内壁与外壁相反是带负电的。这样,Gott认为植入物引起凝血现象是受其表面电荷的影响。他将石墨涂料覆盖在试样表面,做成导电试样,并使其带电后植入血管。当其带正电时,产生血栓;而带上负电时,就一直无血栓生成。更重要的发现是试样不带电时,也无血栓生成。显然,石墨涂料本身是抗血栓生成的. Cott结果发表之后,他的小组和通用原子(General Atomic)碳小组合作研究热介碳与血液的相容性,并把碳的这种相容性和它的晶格结构及表面性质联系起来。出乎意料,先前认为用胶体石墨做成的石墨涂料具有抗血栓生成的观点,后来证明是错误的。这 In the early 1960s, Gott and his colleagues studied the effect of charge on thrombus caused by plastic. Abramson has long found that the important component of the blood is negatively charged. Sawyer also found that the inner and outer walls of blood vessels are negatively charged. Thus, Gott believes that coagulation caused by implants is affected by the surface charge. He will graphite coating on the surface of the sample, made of conductive samples, and make it implanted in the blood vessels. When it is positively charged, it produces a thrombus, whereas when it carries a negative charge, it has been thrombotic-free. The more important finding is that there is no thrombosis when the sample is uncharged. Clearly, the graphite coating itself is anti-thrombotic.After Cott’s results were published, his group worked with the General Atomic carbon team to investigate the compatibility of the thermo-carbon with blood and to incorporate this compatibility of carbon and Its lattice structure and surface properties are linked. Unexpectedly, the previous view that graphite coatings made with colloidal graphite had antithrombotic propositions proved to be erroneous. This