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目的观察慢性阻塞性肺疾病患者(COPD)肺动脉高压变化与肺栓塞关系,为临床诊断提供参考。方法选取2013年2月—2014年2月我院收治的慢性阻塞性肺疾病患者66例,其中合并肺栓塞(PE)40例设为对照组,无肺栓塞(PE)26例设为观察组,比较两组患者肺动脉压力变化及其临床特征。结果两组对比结果显示,对照组下肢非对称性肿胀发生率、血浆D-二聚体阳性情况、超敏CRP水平均高于观察组,对比差异有统计学意义(P<0.05)。结论下肢非对称性肿胀发生率、血浆D-二聚体阳性情况、超敏CRP等指标是COPD合并肺栓塞临床诊断的重要依据,对此需要引起重视并通过相关检查进一步明确诊断。
Objective To observe the relationship between pulmonary hypertension and pulmonary embolism in patients with chronic obstructive pulmonary disease (COPD) and provide a reference for clinical diagnosis. Methods Sixty-six patients with chronic obstructive pulmonary disease admitted to our hospital from February 2013 to February 2014 were enrolled in this study. Forty PE patients with pulmonary embolism (PE) were enrolled in the study. 26 patients without pulmonary embolism (PE) The changes of pulmonary artery pressure and its clinical features were compared between the two groups. Results The comparison between the two groups showed that the incidence of asymmetric swollen limbs, the positive plasma D-dimer and the level of hypersensitive CRP in the control group were significantly higher than those in the observation group (P <0.05). Conclusions The incidence of asymmetric lower limb swelling, positive plasma D-dimer, and hypersensitive CRP are the important evidences for the clinical diagnosis of COPD with pulmonary embolism. Therefore, more attention should be paid to the lower extremity asymmetry and the diagnosis should be further confirmed by related tests.