肾上腺髓质素 (ADM)大量分布于生殖系统的子宫、卵巢、胎盘和胎膜等重要器官和组织 ,对子宫内膜的生长、平滑肌的收缩、颗粒细胞分化、卵子的成熟和释放等具有重要的调节作用 ,参与月经周期、IVF周期、妊娠等重要的生理过程 ,与病理妊娠和肿瘤等生殖系统疾病的发病过程关系密切 ,表明ADM在生殖系统中是重要的内分泌、旁分泌和自分泌因子 Adrenomedullin (ADM) is widely distributed in the reproductive system of uterus, ovaries, placenta and fetal membranes and other important organs and tissues, and is important for endometrial growth, smooth muscle contraction, granulosa cell differentiation, egg maturation and release Regulation of menstrual cycle, IVF cycle, pregnancy and other important physiological processes, and pathological pregnancy and tumor reproductive system disease closely related to the pathogenesis, suggesting that the ADM in the reproductive system is an important endocrine, paracrine and autocrine factors