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本征系指在脑血管意外,特别是脑出血后的一段时间内,出现具有全身免疫性疾病表现的一组症候群而言的。本征病因机理:脑血管意外,特别是脑出血,必定使脑组织遭到破坏。当脑组织自身抗原随血液循环流至周身的免疫系统后,即能以自身抗原来产生自身抗体。如果抗原抗体复合物沉积于身体诸脏器,或激活补体系统,也能引起各种病变反应。实验证明,在脑出血发作后的患者血液中,确有脑抗原物质和自身抗体存在。这就充分说明本系的发生是一自身免疫性疾病。诊断要点 1.在脑出血后的大约2~3个月后,在一般
Intrinsic refers to a group of syndromes that present with a manifestation of a systemic immunodeficiency within a period of time after cerebrovascular accidents, particularly intracerebral hemorrhage. Etiology and pathogenesis: Cerebrovascular accident, especially cerebral hemorrhage, must be destroyed brain tissue. When the brain tissue autoantigen with the blood flow to the whole body’s immune system, that is, to their own antigens to produce autoantibodies. If the antigen-antibody complex deposition in the body organs, or activate the complement system, but also cause a variety of pathological reactions. Experiments show that in the blood of patients after the onset of cerebral hemorrhage, there are indeed brain antigens and autoantibodies exist. This fully shows that the occurrence of this department is an autoimmune disease. Diagnostic points 1. About 2 to 3 months after cerebral hemorrhage, in general