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Let u =(uh, u3) be a smooth solution of the 3-D Navier-Stokes equations in R3× [0, T). It was proved that if u3 ∈ L∞(0, T;˙B-1+3/p p,q(R3)) for 3 < p, q < ∞ and uh∈ L∞(0, T; BMO-1(R3)) with uh(T) ∈ VMO-1(R3), then u can be extended beyond T. Th