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目的:研究血清降钙素原(PCT)联合C-反应蛋白(CRP)检测对菌血症的临床预测价值。方法回顾性调查2014年1月至12月某院出院诊断菌血症患者中入院即抽取血培养及PCT检测患者共计75例,分为社区感染组和院内感染组,观察其首次PCT水平、血培养结果及C-反应蛋白结果,运用ROC曲线评价PCT及C-反应蛋白在菌血症中的应用价值。结果在确诊的75例菌血症患者中社区感染组CRP和PCT比较差异无统计学意义(P>0.05)。PCT预测菌血症ROC曲线下面积最大为0.703显著高于C-反应蛋白0.595,差异有统计学意义(P<0.05)。结论相比较C-反应蛋白和血培养,PCT检测对菌血症有较好的敏感性,可作为早期诊断菌血症的参考依据。
Objective: To study the clinical predictive value of serum procalcitonin (PCT) combined with C-reactive protein (CRP) test on bacteremia. Methods A total of 75 patients admitted to hospital from September 2014 to December 2004 were enrolled in this study, namely blood culture and PCT tests. A total of 75 patients were divided into community infection group and nosocomial infection group. The first PCT level and blood Culture results and C-reactive protein results, the use of ROC curve evaluation of PCT and C-reactive protein in the application of bacteremia value. Results There was no significant difference in the CRP and PCT between the community-acquired infection groups in the 75 patients with confirmed bacteremia (P> 0.05). The area under the ROC curve of PCT prediction bacteremia was significantly higher than that of C-reactive protein 0.595 (0.703), the difference was statistically significant (P <0.05). Conclusion Compared with C-reactive protein and blood culture, PCT test has good sensitivity to bacteremia and can be used as reference for early diagnosis of bacteremia.