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5. EFFECTS OF MUTATION AND EXPRESSION OF PTEN GENE mRNA ON TUMORIGENESIS AND PROGRESSION OF EPITHELIAL

EFFECTS OF MUTATION AND EXPRESSION OF PTEN GENE mRNA ON TUMORIGENESIS AND PROGRESSION OF EPITHELIAL

来源 :中国医学科学杂志：英文版 | 被引量 : 0次 | 上传用户：yang20090907

【摘 要】

：

Objective To investigate the mutation and expression of tumor suppressor gene-PTEN mRNA and explore their roles in tumorigenesis and progression of ovarian canc

【作 者】

：

陈颖  郑华川  杨雪飞  孙丽梅  辛彦 

【机 构】

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ShenyangHospitalofObstetricsandGynecology,TheFourthLaboratory

【出 处】

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中国医学科学杂志：英文版

【发表日期】

：

2004年1期

【关键词】

：

卵巢癌 PTEN 肿瘤生成 癌前病变 RT-PCR ovarian neoplasmsPTEN genemutationgene expression 

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Objective To investigate the mutation and expression of tumor suppressor gene-PTEN mRNA and explore their roles in tumorigenesis and progression of ovarian cancer. Methods Mutated exon 5 of PTEN gene was examined in normal ovary (n = 5), ovarian cyst (n =

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