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目的探讨使用小剂量雌激素预防绝经后妇女泌尿系感染发作患者的临床疗效。方法选取本院2011年5月~2012年5月收治的66例绝经后妇女泌尿系感染发作患者为研究对象,将其随机分成A组与B组,A组36例患者给予抗生素进行治疗,B组30例患者给予小剂量的雌三醇软膏进行治疗,半年后观察比较两组治疗效果。结果 B组患者雌二醇E2水平、阴道健康评分及泌尿系感染治疗有效率明显较A组提升,阴道环境pH值明显下降,比较差异均具有统计学意义(P<0.05)。结论使用小剂量雌激素对于预防绝经后妇女泌尿系感染发作患者的临床疗效显著,值得应用推广。
Objective To investigate the clinical efficacy of using small doses of estrogen in the prevention of urinary tract infection in postmenopausal women. Methods Sixty-six patients with urinary tract infection who were treated in our hospital from May 2011 to May 2012 were selected as study subjects and randomly divided into A group and B group. A group of 36 patients were treated with antibiotics, and B Group of 30 patients given small doses of estriol ointment for treatment, six months after the observation and treatment of two groups were compared. Results The estradiol E2 level, vaginal health score and urinary tract infection in group B were significantly higher than those in group A and vaginal environment. The differences were statistically significant (P <0.05). Conclusions The use of small doses of estrogen for the prevention of urinary tract infection in postmenopausal women with clinical significant effect, it is worth to promote the application.