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目的:对甲硝唑栓联合结合雌激素软膏治疗老年性阴道炎患者的疗效进行研究。方法:2012年2月~2014年2月我院妇产科共收治87例老年性阴道炎患者,应用随机双盲法将其分为研究组(45例)与对照组(42例),对照组仅应用甲硝唑栓,研究组应用甲硝唑栓联合结合雌激素软膏。结果:研究组总治疗有效率95.6%明显高于对照组的69.0%,研究组FSH(150.05±50.24)与E2(33.42±14.16)等指标改善显著优于对照组的(107.42±30.08)与(46.48±13.17),对比p均<0.05。结论:应用甲硝唑栓联合结合雌激素软膏治疗老年性阴道炎患者,显著提高临床有效率,并提高患者FSH水平,降低E2水平,并减少不良反应。
Objective: To study the curative effect of metronidazole suppository combined with estrogen ointment in the treatment of senile vaginitis. Methods: From February 2012 to February 2014, 87 patients with senile vaginitis were admitted to our department of obstetrics and gynecology. They were divided into study group (45 cases) and control group (42 cases) by random double-blind method. Group only metronidazole suppository, the study group applied metronidazole suppository combined with estrogen ointment. Results: The total effective rate of the study group was 95.6%, which was significantly higher than that of the control group (69.0%). The improvement of FSH (150.05 ± 50.24) and E2 (33.42 ± 14.16) in the study group was significantly better than that of the control group (107.42 ± 30.08) 46.48 ± 13.17), both p <0.05. Conclusion: The application of metronidazole suppository combined with estrogen ointment in the treatment of senile vaginitis patients, significantly improve the clinical efficiency, and improve patients with FSH levels, reduce E2 levels, and reduce adverse reactions.