肝细胞生长因子是一种多肽生长因子,与其受体结合后,具有强促分裂、组织成形、诱导肿瘤细胞迁移、侵袭以及诱导血管生成等作用。肝细胞生长因子受体c-Met广泛存在于多种正常组织细胞和体内外恶性肿瘤细胞内,肝细胞生长因子与其受体和肿瘤的发生、发展以及肿瘤新生血管形成有密切关系。 Hepatocyte growth factor is a polypeptide growth factor, with its receptor binding, with strong mitosis, tissue forming, inducing tumor cell migration, invasion and induction of angiogenesis and so on. The hepatocyte growth factor receptor c-Met is widely found in a variety of normal tissue cells and malignant cells in vivo and in vitro. Hepatocyte growth factor is closely related to the occurrence and development of its receptor and tumor, as well as tumor angiogenesis.