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目的探讨肝脏局灶性结节增生(FNH)磁共振成像(MRI)的典型表现及与之相应的病理特点。方法回顾性分析6例经病理证实的肝脏FNH患者的MRI表现,总结其影像特征,并与病理进行对照。结果 6例肝脏FNH患者的MRI均表现为孤立信号病灶,5个病灶T1WI为等或等低信号,T2WI为等信号、稍高信号,1个病灶T1WI为低信号、T2WI为高信号,而中央瘢痕在T2WI为高信号;增强扫描病灶动脉期明显均匀强化,门脉期及延迟期增强程度下降;而中央瘢痕延迟强化呈高信号。病理上FNH的实性部分由异常排列的肝细胞、Kupffer细胞以及毛细胆管组成,其内有纤维间隔,增生的纤维组织间隔向四周呈放射状将肝组织分隔成结节状肿块,而病灶中心为星芒状纤维瘢痕组织。结论典型肝脏FNH的MRI影像表现可以反映其病理特点。
Objective To investigate the typical manifestations of liver focal nodular hyperplasia (FNH) magnetic resonance imaging (MRI) and its corresponding pathological features. Methods The MRI features of 6 FNH patients confirmed by pathology were retrospectively analyzed. The imaging features were summarized and compared with the pathology. Results MRI of 6 patients with liver FNH showed isolated signal lesions, T1WI of 5 lesions were equal or low signal, T2WI was equal signal, slightly higher signal, T1WI of 1 lesion was low signal, T2WI was high signal, while central Scar in T2WI is a high signal; enhancement of the lesion in the arterial phase was significantly uniform enhancement, decreased portal phase and delayed phase decreased; while the central scar delayed enhancement was high signal. Pathological FNH of the solid part of the abnormal arrangement of the liver cells, Kupffer cells and the bile duct composed of fibers within the interval, hyperplastic fibrous tissue spaced radially to the surrounding liver tissue is divided into nodular mass, and the lesion center is Star-shaped fiber scar tissue. Conclusion MRI findings of typical liver FNH can reflect its pathological features.