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自Anderson等[1]1989年首次提出神经干细胞(neural stem cells,NSC)概念并用实验证实其存在以后,人们开始寻找治疗神经系统疾病的新途径。研究表明NSC、胚胎干细胞、骨髓间充质干细胞(mes-enchymal stem cells,MSCs)对脑缺血均有治疗作用。MSCs指骨髓间质中具有自我复制和多向分化潜能的干细胞,在特定条件下不仅可分化为中胚层细胞,
Since Anderson et al [1] first proposed the concept of neural stem cells (NSCs) in 1989 and confirmed its existence by experiments, people began to search for new ways to treat the diseases of the nervous system. Studies have shown that NSC, embryonic stem cells, bone marrow mesenchymal stem cells (mes-enchymal stem cells, MSCs) have a therapeutic effect on cerebral ischemia. MSCs refer to stem cells that have the potential of self-replication and multi-directional differentiation in bone marrow stroma. Under certain conditions, MSCs can differentiate into mesodermal cells,