论文部分内容阅读
2(5H)-呋喃酮结构单元广泛存在于天然产物中,同时许多2(5H)-呋喃酮类化合物也是重要的有机合成中间体.因此,基于常见2(5H)-呋喃酮的有机合成研究近年来引起了人们的关注,尤其是金属催化的2(5H)-呋喃酮反应的地位日趋彰显重要,从而成为众多化学工作者的研究热点.按照反应类型的不同,对近年来金属催化的2(5H)-呋喃酮反应的研究进展进行了综述,主要包括Sonogashira,Suzuki,Stille等偶联反应,以及Michael加成反应、Friedel-Crafts烷基化反应、Baylis-Hillman反应、亲核取代反应、还原反应等.
2 (5H) -furanone structural units are widely found in natural products, and many 2 (5H) -furanones are also important organic synthesis intermediates. Therefore, organic syntheses based on common 2 (5H) -furanones In recent years, it has attracted people’s attention, especially the role of metal-catalyzed 2 (5H) -furanone reaction becoming more and more important, which has become a hot research topic of many chemists.According to the different reaction types, (5H) -furanone, including Sonogashira, Suzuki, Stille and other coupling reactions as well as Michael addition reaction, Friedel-Crafts alkylation, Baylis-Hillman reaction, nucleophilic substitution reaction, Reduction reaction and so on.