经前期综合征(PMS)累及大部分妇女。它严重到可以暂时搅扰人与人的关系。工作效率降低者占相当高的百分数。查阅本病过去的文献,没有找到一个能充分解释PMS的不同症状的假说。看来其它的神经内分泌变化可使女性素过量或黄体酮缺乏。控制性类脂醇水平疗法,仅取得有限的成功。虽然口服避孕药治疗,能改善月经不调,它对PMS本身症状有不利作用,有少数病人的症状得以减轻,但较多的病人则症状加重。黄体酮治疗PMS的结果变化很大,且常失败。没有双盲研究去证实其疗效,连续使用黄体酮是不值提倡的。维生素缺乏的致病作用也是可疑的。维生素A应该停止使用。用维生素B_6也有争论,它只能作为安慰剂使用。除非对照研究能显示其疗效。葡萄糖代谢变异作为 Premenstrual syndrome (PMS) involving most women. It is serious enough to temporarily disturb the relationship between people. Lower work efficiency accounted for a very high percentage. Check the literature of the disease, did not find a can fully explain the different symptoms of PMS hypothesis. It appears that other neuroendocrine changes can make women overdose or lack of progesterone. Controlled-lipid level therapy achieved only limited success. Although oral contraceptive treatment can improve irregular menstruation, it has an adverse effect on the symptoms of PMS itself, and the symptoms of a few patients are alleviated. However, the symptoms of more patients are aggravated. The results of progesterone treatment of PMS vary widely and often fail. There is no double-blind study to confirm its efficacy, continuous use of progesterone is not worth promoting. The pathogenic role of vitamin deficiency is also suspicious. Vitamin A should stop using. Vitamin B_6 is also debated, it can only be used as a placebo. Unless controlled studies can show its efficacy. As a metabolic variation of glucose