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本组对上海市徐汇区1987年2月至1988年1月出生的活产婴儿8662名(男4428名,女4214名),进行先天性心脏病(先心病)流行病学调查,一年中随访六次。先心病发病率为7.16‰,其中室间隔缺损最多见,占59.68％,室间隔缺损自然闭合率为27.03％。先心病发病因素初步调查结果表明与母亲年龄、胎次、先兆流产史、妊娠毒血症史和婴儿出生月份无明显关系,而与母亲妊娠3月内上呼吸道感染及先心病家族史有明显关系。
The group of 8662 live births (4428 males and 4214 females) born in Xuhui District of Shanghai from February 1987 to January 1988 were investigated for epidemiology of congenital heart disease (CHD) Follow-up six times. The incidence of congenital heart disease was 7.16 ‰, of which the most common ventricular septal defect, accounting for 59.68%, 27.03% of the natural closure rate of ventricular septal defect. Preliminary findings of the incidence of congenital heart disease showed no significant relationship with the mother’s age, parity, history of threatened abortion, history of gestational toxemia and the month of birth but had a significant relationship with the mother’s upper respiratory tract infection and family history of congenital heart disease in March of pregnancy .