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目的探讨小儿氨酚黄那敏颗粒对急性上呼吸道感染效果影响。方法选择2015年4月-2016年5月吉林市北华大学附属医院儿内科门诊确诊为急性上呼吸道感染患儿276例,按就诊顺序奇偶数分为观察组和对照组,各138例。对照组口服利巴韦林颗粒。观察组口服小儿氨酚黄那敏颗粒同时给予利巴韦林气雾剂。比较两组治疗5 d后疗效、热退时间、鼻塞缓解时间、流涕缓解时间及咳嗽缓解时间。结果治疗5 d后,观察组有效率明显高于对照组,差异有统计学意义(P<0.05);观察组患儿退热时间、鼻塞缓解时间、流涕缓解时间及咳嗽缓解时间均短于对照组,差异有统计学意义(P<0.01)。治疗期间对照组有2例出现白细胞减少,观察组未出现不良反应。结论小儿氨酚黄那敏颗粒联合利巴韦林气雾剂治疗急性上呼吸道感染疗效确切。
Objective To investigate the effects of paracetamol, Huangnaomin granule on acute upper respiratory tract infection. METHODS: From April 2015 to May 2016, 276 children with acute upper respiratory tract infection were diagnosed in Department of Pediatric Internal Medicine, Affiliated Hospital of Beihua University, Jilin Province, and were divided into observation group and control group according to the order of treatment. Each group had 138 cases. Control group oral ribavirin particles. The observation group oral administration of paracetamol Huangnaomin particles while given ribavirin aerosol. After 5 days of treatment, the curative effect, thermal withdrawal time, relief time of nasal obstruction, time to relieve runny nose and cough relief time were compared. Results After 5 days of treatment, the effective rate of the observation group was significantly higher than that of the control group (P <0.05). The observation group had shorter antipyretic time, relief time of nasal obstruction, longer time to relieve runny nose and longer cough relief The control group, the difference was statistically significant (P <0.01). Two cases of leukopenia in the control group during the treatment, the observation group did not appear adverse reactions. Conclusion Pediatric Paracetamol Huang Namin granules combined with ribavirin aerosol treatment of acute upper respiratory tract infection is effective.