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目的:探讨中西医结合治疗高血压脑出血并发肺部感染患者血清炎症因子水平的临床观察。方法:纳入的70例高血压脑出血并发肺部感染患者根据随机数字表法随机分为中西医组和西医组各35例。中西医组给予中西医结合治疗,西医组给予常规西药治疗。疗程均为14 d。结果:中西医组治疗总有效率(85.71%)较西医组(62.86%)高,且有统计学意义(P<0.05);中西医组治疗后症状积分较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后体征积分较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后血清hs-CRP、IL-6、TNF-α较治疗前减少(P<0.05),且低于西医组(P<0.05);中西医组治疗后收缩压、舒张压较治疗前下降(P<0.05),且低于西医组(P<0.05);而中西医组治疗后血氧饱和度较治疗前上升(P<0.05),且高于西医组(P<0.05);中西医组平均住院时间短于西医组(P<0.05);两组用药均未见严重不良反应。结论:中西医结合治疗高血压脑出血并发肺部感染患者可降低血清炎症因子水平,改善炎症状态,且疗效明显。
Objective: To investigate the clinical observation of serum inflammatory factors in patients with pulmonary hemorrhage complicated by Integrative Chinese and Western Medicine. Methods: Seventy patients with hypertensive intracerebral hemorrhage complicated with pulmonary infection were randomly divided into three groups (35 cases in each group) according to random number table. Western medicine group to give Integrative Medicine, Western medicine group to give conventional Western medicine. The course of treatment was 14 days. Results: The total effective rate of TCM and WM was 85.71% higher than that of WMD (62.86%) (P <0.05), and the symptom scores of TCM and WM decreased after treatment (P <0.05) (P <0.05), and lower than Western medicine group (P <0.05). After treatment, the score of Chinese medicine and western medicine group was lower than that of Western medicine group (P <0.05) (P <0.05), and lower than Western medicine group (P <0.05). The systolic pressure and diastolic pressure of the Western medicine group were lower than those before treatment (P <0.05), and lower than Western medicine group (P <0.05), while Western medicine group after treatment, oxygen saturation than before treatment increased (P <0.05), and higher than Western medicine group (P <0.05); Chinese and Western medicine group average length of stay shorter than Western medicine group P <0.05). No adverse reactions were found in the two groups. Conclusion: Integrative treatment of hypertensive intracerebral hemorrhage complicated with pulmonary infection can reduce the level of serum inflammatory cytokines, improve the inflammatory state, and the curative effect is obvious.