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在9只失血性休克狗(平均血压维持在40mmHg)观察其球结膜微循环,并定期从股动脉采血检查血液和血浆比粘度、红细胞比容、血小板聚集和红细胞变形能力。结果:一、微循环反应非常敏感,放血后数分钟球结膜微动收缩,血流速度变慢,红细胞出现聚集;休克期镜下可见毛细血管数目减少,血流停滞,红细胞重度聚集。二、血液流变学检查:放血停止后,血液和血浆比粘度,红细胞比容均明显下降;血小板聚集加强;红细胞变形能力的变化发生较晚,休克后一小时开始降低。三、回输失去的血液和生理盐水后,微循环和血液流变学诸指标都趋向恢复。作者分析了失血性休克狗微循环和血液流变学的关系。
Nine hemorrhagic shock dogs (mean blood pressure was maintained at 40 mmHg) were observed for bulbar conjunctival microcirculation and blood and plasma specific viscosity, hematocrit, platelet aggregation and erythrocyte deformability were examined periodically from the femoral artery. Results: First, the microcirculation reaction is very sensitive, a few minutes after excretion of the conjunctival microvascular contraction, blood flow slows down, erythrocyte aggregation; shock period, the visible decrease in the number of capillaries, blood flow stagnation, severe accumulation of red blood cells. Second, hemorheology examination: bleeding stopped, the blood and plasma viscosity, hematocrit were significantly decreased; platelet aggregation strengthened; changes in erythrocyte deformability occurred later, one hour after shock began to reduce. Third, the loss of return to the blood and saline, microcirculation and hemorheology all indicators tend to recover. The authors analyzed the relationship between hemorheology and microcirculation in hemorrhagic shock dogs.