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现在常认为急性粒细胞白血病(急性粒)是一种细胞群的疾病,其正常骨髓被异常的细胞群的过度增生所代替。用化疗导致缓解时,毁坏了大多数异常细胞,使残留的正常骨髓细胞获得再生。如不再治疗或无有效的维持疗法时,在正常骨髓再被白血病细胞群的过度增生所代替以前,病人可享有一段时期的健康。有很少一部分急性粒病例,可在预先存在的血液病的基础上发生,即为白血病前期。此病名尚无准确的定义,但很清楚,它包括一系列骨髓疾病,主要分为二组:(1)相对非特异性血液学异常组(如顽固性贫血、获得性含铁母细胞性贫血,常伴有白细胞异
It is now commonly accepted that acute myeloid leukemia (acute granulocyte) is a disease of a cell population whose normal bone marrow is replaced by an overgrowth of an abnormal cell population. Chemotherapy lead to remission, the destruction of most of the abnormal cells, the residual normal bone marrow cells to obtain regeneration. Without treatment or effective maintenance therapy, the patient may enjoy a period of health before the normal bone marrow is replaced by the hyperplasia of the leukemic cell population. A small number of acute granulomatous cases can occur on the basis of pre-existing hematological disorders, ie, pre-leukemia. The disease name is not defined precisely, but it is clear that it includes a series of bone marrow diseases that fall into two major groups: (1) relative nonspecific hematologic abnormalities (such as refractory anemia, acquired iron-bearing anemia, Often accompanied by different leukocytes