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目的探讨中青年年龄组冠心病(coronary heart disease,CHD)患者的临床及冠状动脉造影(CAG)特点。方法从我院2010.6-2011.6期间CHD患者中选取587例,根据年龄分为中青年组(<60岁,n=243)和老年组(≥60岁,n=344),对两组患者一般资料、血生化指标及CAG结果进行回顾性分析。结果两组患者均以男性为主。中青年组吸烟比例、冠心病家族史阳性率较老年组高(P<0.05),中青年组的血浆尿酸水平明显低于老年组(P<0.05),中青年组以单支病变为主,老年组则以多支病变较多,差异有统计学意义(P<0.05),并且中青年组右冠状动脉病变构成比明显低于老年组(P<0.05)。结论中青年组和老年组CHD有不同的临床和CAG特点,采取有针对性的CHD防治措施,对合理防治冠状动脉病变的发生和发展有重要意义。
Objective To investigate the clinical and coronary angiography (CAG) features of patients with coronary heart disease (CHD) in middle-aged and adolescent age groups. Methods A total of 587 CHD patients from our hospital from June 2010 to June 2011 were selected and divided into two groups according to their ages: younger (n = 243) and elderly (≥60 years, n = 344) , Blood biochemical indicators and CAG results were retrospectively analyzed. Results Both groups were predominantly male. The prevalence of smoking in middle-aged and young people and the positive rate of family history of coronary heart disease were higher than those in the elderly group (P <0.05). The levels of plasma uric acid in middle-aged and younger patients were significantly lower than those in the elderly group (P <0.05) The elderly group with multiple lesions, the difference was statistically significant (P <0.05), and young and middle-aged group of right coronary artery lesions was significantly lower than the old group (P <0.05). Conclusion There are different clinical and CAG features of CHD in middle-aged and young patients. Taking targeted prevention and treatment of CHD is of great significance for the prevention and treatment of coronary artery disease.